KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF23
All Species:
13.64
Human Site:
S74
Identified Species:
30
UniProt:
Q9BUL5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUL5
NP_077273.2
403
43818
S74
R
G
E
S
A
A
D
S
D
G
W
D
S
A
P
Chimpanzee
Pan troglodytes
XP_001169367
403
43830
S74
R
G
E
S
A
A
D
S
D
G
W
D
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001106687
403
43802
S74
R
G
E
S
A
A
D
S
D
G
W
D
S
A
P
Dog
Lupus familis
XP_848850
399
43241
L80
W
D
S
A
P
S
D
L
R
T
I
Q
T
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSN5
401
43528
S74
R
G
E
S
A
A
D
S
D
G
W
D
S
A
P
Rat
Rattus norvegicus
Q6AY75
334
36213
C38
I
E
D
F
N
K
F
C
S
F
V
L
A
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519103
331
36738
R35
V
K
A
P
A
A
G
R
D
E
A
T
L
M
G
Chicken
Gallus gallus
XP_425732
284
31676
Frog
Xenopus laevis
Q0IHB0
269
29110
Zebra Danio
Brachydanio rerio
Q5BJ10
296
33413
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785537
187
21302
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
94.2
N.A.
94
77.6
N.A.
27.7
28.7
39.9
36.2
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.7
99.5
95.5
N.A.
95.5
78.9
N.A.
40.2
39.9
49.6
46.4
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
100
100
6.6
N.A.
100
0
N.A.
20
0
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
13.3
N.A.
20
0
0
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
46
46
0
0
0
0
10
0
10
37
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
46
0
46
0
0
37
0
0
0
% D
% Glu:
0
10
37
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
10
0
0
10
0
0
0
10
0
% F
% Gly:
0
37
0
0
0
0
10
0
0
37
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
37
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
37
0
10
0
37
10
0
0
0
37
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _